home *** CD-ROM | disk | FTP | other *** search
-
- Table 6-3. Clinical pharmacokinetics and dosages of the non-thiazide
- diuretics. Presc Cat contains the controlled drug (Rx) <tab1-1>
- and FDA pregnancy safety category codes (B,C) <tab1-2>
- To calculate dose for an over/underweight patient: <newcalc>
- _________________________________________________________________________
- Drug Recommended Time to Duration
- Available Dose Dosing onset (half-life) Presc
- as Interval (hrs) (hrs) Cat Notes
- _______________(mg)__(hrs)_______________________________________________
-
- LOOP DIURETICS
- Bumetanide
- Bumex: 0.5,1 mg tabs; 0.5 mg/2 mL amp for IV or IM injection
- 0.5-2 12-24 0.1-1 2-6 Rx;(C) 1
- Ethacrynic acid
- Edecrin: 25,50 mg tabs; 50 mg powder/vial for IV (only) injection
- 50-100 24 0.1-0.5 2-8 Rx;(C) 1
- Furosemide
- generic, Lasix: 20,40,80 mg tabs; 10 mg/mL oral suspension;
- 10 mg/mL for IM or IV injection
- 20-80 12-24 0.1-1 2-8 Rx;(C) 1
-
- (End key for footnotes, PgDn for more drugs)
-
-
- POTASSIUM-SPARING DIURETICS
- ────────────────────────────────────────────────────────────────────────
- Drug Dose Interval Onset(h) Dur(h) Cat Notes
- ────────────────────────────────────────────────────────────────────────
- Amiloride
- Midamor: 5 mg tabs
- 5-20 24 2 24 Rx;B
- Spironolactone
- generic, Aldactone: 25,50,100 mg tabs
- 25-200 24 24-48 48-72 Rx;(C)
- Triamterene
- generic, Dyrenium: 50,100 mg tabs
- 100-150 12 2 12-16 Rx;(C)
-
-
-
-
-
-
-
-
- (PgDn key for more drugs)
-
-
- CARBONIC ANHYDRASE INHIBITORS
- ────────────────────────────────────────────────────────────────────────
- Drug Dose Interval Onset(h) Dur(h) Cat Notes
- ────────────────────────────────────────────────────────────────────────
- Acetazolamide
- generic, Diamox: 125,250 mg tabs; 500 mg sustained
- release caps; 500 mg/vial for injection
- 250-500 12-24 2-3 Rx;(C) 2
- Dichlorphenamide
- Daranide: 50 mg tabs
- 25-50 8-24 1-2 6-12 Rx;(C) 3,4
- Methazolamide
- Neptazane: 50 mg tabs
- 50-100 8-12 2-3 10-18 Rx;(C) 4
-
-
-
-
-
-
-
- (End key for footnotes, PgDn key for more drugs)
-
- OSMOTIC DIURETICS
-
- ────────────────────────────────────────────────────────────────────────
- Drug Dose Interval Onset(h) Dur(h) Cat Notes
- ────────────────────────────────────────────────────────────────────────
- see manufacturer's recommendations for the specific indication
- Mannitol (IV use only) Rx;(C)
- generic, Osmitrol: available in 5, 10, 15, 20, and 25% solutions
- Isosorbide (Oral use only) Rx;(B)
- Ismotic: available as 45% (0.45g/mL) solution
- Glycerine (Oral use only) Rx;C
- Glyrol: 75% (0.94g/mL) solution
- Osmolglyn: 50% (0.6g/mL) solution Urea (IV use only) Rx;C
- Ureaphil: 40 g/150 mL solution
- =========================================================================
-
-
-
-
-
-
- (PgDn key for footnotes)
-
- FOOTNOTES:
- 1. Onset of action within minutes after injection; 1 hour after oral ad-
- ministration.
- 2. Given daily in the dosages listed for the treatment of glaucoma and
- epilepsy; 2 days out of every 3 at 1/2 to 1/3 the listed dosage in edema
- due to congestive failure.
- 3. Loading dose 4 times greater suggested until desired effect is
- achieved.
- 4. Indicated for glaucoma; not recommended for use as a diuretic.
-
-
-
-
-
-
-
-
-
-
-
-
- (Home key to return to top of file)